Statins and muscle damage
نویسندگان
چکیده
منابع مشابه
Statins, Muscle Disease and Mitochondria
Cardiovascular disease (CVD) accounts for >17 million deaths globally every year, and this figure is predicted to rise to >23 million by 2030. Numerous studies have explored the relationship between cholesterol and CVD and there is now consensus that dyslipidaemia is a causal factor in the pathogenesis of atherosclerosis. Statins have become the cornerstone of the management of dyslipidaemia. S...
متن کاملPotential adverse effects of statins on muscle.
M any people have high blood cholesterol that may lead to coronary heart disease (CHD). A multifaceted approach consisting of diet, exercise, and pharmacological management is recommended to lower the risk of CHD.1 Elevated low-density lipoprotein-cholesterol (LDL-C) has been established as a major cause of CHD.1 The group of cholesterol-lowering drugs known as statins (3-hydroxy3-methylglutary...
متن کاملEffect of statins on skeletal muscle function.
BACKGROUND Many clinicians believe that statins cause muscle pain, but this has not been observed in clinical trials, and the effect of statins on muscle performance has not been carefully studied. METHODS AND RESULTS The Effect of Statins on Skeletal Muscle Function and Performance (STOMP) study assessed symptoms and measured creatine kinase, exercise capacity, and muscle strength before and...
متن کاملSafety of statins: effects on muscle and the liver.
Although statin drugs can have adverse effects on muscles and the liver, these effects are uncommon. Caution is warranted in patients at higher risk, ie, those who are elderly, frail, or small; have multisystem disease; are receiving immunosuppressive drugs or other medications that interact with statins; or are receiving higher doses of a statin.
متن کاملMuscle damage: Scientific fundamentals.
TO THE EDITOR: I read the recent article by Peake et al. (4) entitled “Muscle damage and inflammation during recovery from exercise” with great interest. I would suggest adding more information about muscle damage, because in my opinion the authors talked about muscle damage minimally. The authors stated (4): “. . . Concentric muscle contractions do not cause exercise-induced muscle damage.” Bu...
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ژورنال
عنوان ژورنال: Australian Prescriber
سال: 2003
ISSN: 0312-8008,1839-3942
DOI: 10.18773/austprescr.2003.054